Details

Autor(en) / Beteiligte

• Bao, M
• Shi, D Y
• Shi, H X
• Liu, X L
• Duan, M H
• Zhuang, J L
• Du, X
• Qin, L
• Hui, W H
• Liang, R
• Wang, M F
• Chen, Y
• Li, D Y
• Yang, W
• Tang, G S
• Zhang, W H
• Kuang, X
• Su, W
• Han, Y Q
• Chen, L M
• Xu, J H
• Liu, Z G
• Huang, J
• Zhao, C T
• Tong, H Y
• Hu, J D
• Chen, C Y
• Chen, X Q
• Xiao, Z J
• Jiang, Q

Titel

Health-related quality of life and its associated variables in Chinese patients with Philadelphia-negative myeloproliferative neoplasms

Ist Teil von

• Zhōnghuá xuèyèxué zázhì, 2021-12, Vol.42 (12), p.985

Ort / Verlag

China

Erscheinungsjahr

2021

Quelle

MEDLINE

Beschreibungen/Notizen

• To explore health-related quality of life (HRQoL) and identify its associated variables in Chinese patients with Philadelphia-negative myeloproliferative neoplasms (MPNs) . In this cross-sectional study, anonymous questionnaires were distributed to adult patients with MPNs to assess symptom burden measured by MPN-10 and HRQoL measured by Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30) . The data from 1405 respondents with MPNs, including 645 (45.9%) with essential thrombocythemia (ET) , 297 (21.1%) with polycythemia vera (PV) , and 463 (33.0%) with myelofibrosis (MF) , were analyzed. 646 (46.0%) respondents were male. The median age was 56 (range, 18-99) years. The mean MPN-10 scores were 13.0±12.7, 15.0±14.7, and 21.0±16.6 ( <0.001) , and the physical component summary (PCS) and mental component summary (MCS) scores were 48.0±8.5, 47.0±9.0, and 42.0±10.0 ( <0.001) and 51.0±