Details

Autor(en) / Beteiligte

• Yamashita, Yo-ichi
• Yamao, Takanobu
• Nakao, Yosuke
• Miyata, Tatsunori
• Ikegami, Yasuhiro
• Yamane, Soichiro
• Ito, Taiga
• Furukawa, Taku
• Cho, Jaeyong
• Wu, Fanqi
• Fujie, Yasumitsu
• Arima, Mitsuru
• Aishima, Shinichi
• Ijima, Hiroyuki
• Baba, Hideo

Titel

Efficacy of a newly developed bioabsorbable pancreatic clip for distal pancreatectomy in swine

Ist Teil von

• Surgery today (Tokyo, Japan), 2022-07, Vol.52 (7), p.1109-1114

Ort / Verlag

Singapore: Springer Nature Singapore

Erscheinungsjahr

2022

Link zum Volltext

Quelle

SpringerLink (Online service)

Beschreibungen/Notizen

• Purpose At present, ≥ 20% of patients experience clinically relevant postoperative pancreatic fistula (POPF) after distal pancreatectomy (DP). Methods We developed a new bioabsorbable pancreatic clip (BioPaC) made of polycaprolactone that does not crush the pancreatic parenchyma during occlusion of the pancreatic stump. We confirmed the efficacy of this BioPac in a porcine DP model and compared it to a linear stapling device (Reinforce®). Results Pigs were killed at 1 month after DP. In the BioPaC group, all swine ( n  =  3 ) survived well without POPF. In the Reinforce® group ( n  =  2 ), one pig died early at postoperative day 7 with Grade C POPF (amylase 43 700 U/l), and the other survived until 1 month at scarification with biochemical leakage of POPF (amylase 3 725 U/l). Pathologically, the main pancreatic duct and pancreatic parenchyma were well closed by BioPaC. Conclusion The newly developed BioPaC is effective in a porcine DP model.