Details

Autor(en) / Beteiligte

• Mayland, Erica
• Curry, Joseph M.
• Wax, Mark K.
• Thomas, Carissa M.
• Swendseid, Brian P.
• Kejner, Alexandra E.
• Kain, Joshua J.
• Cannady, Steven B.
• Miles, Brett A.
• DiLeo, Michael
• McMullen, Caitlin
• Tasche, Kendall
• Ferrandino, Rocco M.
• Sarwary, Juliana
• Petrisor, Daniel
• Sweeny, Larissa

Titel

Impact of preoperative and intraoperative management on outcomes in osteoradionecrosis requiring free flap reconstruction

Ist Teil von

• Head & neck, 2022-03, Vol.44 (3), p.698-709

Ort / Verlag

Hoboken, USA: John Wiley & Sons, Inc

Erscheinungsjahr

2022

Quelle

MEDLINE

Beschreibungen/Notizen

• Background Perioperative management of advanced osteoradionecrosis of the head and neck requiring free flap (FF) reconstruction varies. Our objectives included assessment of practice patterns and outcomes. Methods Multi‐institutional, retrospective review of FF reconstruction for head and neck osteoradionecrosis (n = 260). Results Administration of preoperative antibiotics did not correlate with reduction in postoperative complications. Preoperative alcohol use correlated with higher rates of hardware exposure (p = 0.03) and 30‐day readmission (p = 0.04). Patients with FF compromise had higher TSH (p = 0.04) and lower albumin levels (p = 0.005). Prealbumin levels were lower in patients who required neck washouts (p = 0.02) or a second FF (p = 0.03). TSH levels were higher in patients undergoing postoperative debridement (p = 0.03) or local flap procedures (p = 0.04). Conclusion Malnutrition, hypothyroidism, and substance abuse correlated with a higher incidence of postoperative wound complications in patients undergoing FF reconstruction for advanced osteoradionecrosis. Preoperative antibiotics use did not correlate with a reduction in postoperative wound complications.