Details

Autor(en) / Beteiligte

• He, Lu-Xi
• He, Liang-Ying
• Gao, Fang-Zhou
• Wu, Dai-Ling
• Ye, Pu
• Cheng, Yu-Xiao
• Chen, Zi-Yin
• Hu, Li-Xin
• Liu, You-Sheng
• Chen, Jun
• Ying, Guang-Guo

Titel

Antibiotics, antibiotic resistance genes and microbial community in grouper mariculture

Ist Teil von

• The Science of the total environment, 2022-02, Vol.808, p.152042-152042, Article 152042

Ort / Verlag

Netherlands: Elsevier B.V

Erscheinungsjahr

2022

Quelle

MEDLINE

Beschreibungen/Notizen

• Increasing use of feed and medicine in mariculture could cause negative environmental impacts such as habitat modification, microbial disease development and antibiotic resistance. Here we investigated contamination of antibiotics and antibiotic resistance genes (ARGs), and composition of microbial community in grouper mariculture systems in Hainan province, China. Results showed detection of various antibiotic residues with the dominance of fluoroquinolones and tetracyclines in the six grouper cultivation systems. The concentrations of the detected antibiotics in the grouper mariculture water were significantly higher than those in the original seawater. Some of the detected antibiotics such as enrofloxacin, ciprofloxacin, ofloxacin, oxytetracycline and erythromycin in the mariculture water and/or sediment would pose high resistance selection risks. Sulfonamides resistance genes sul1 and sul2 were found to be predominant in water and sediment, while tetracycline resistance genes were prevalent in fish gill and gut. The dominant bacterial phyla in water and sediments were Bacteroides, Actinomycetes, and Proteobacteria, while the dominant ones in fish gill and gut were the Proteobacteria. Genera of Vibrio and Mycobacterium in the core microbiota were important zoonotic pathogens, and there was a significant positive correlation between Vibrio and ARGs. Phyla of Proteobacteria, Actinomyces, and Cyanobacteria were positively correlated to ARGs, indicating that these microorganisms are potential hosts of ARGs. The putative functions of microbiome related to antibiotic resistance and human diseases were significantly higher in fish than in the mariculture environment. This study suggests that mariculture system is a reservoir of ARGs, and the use of antibiotics in mariculture could induce the increase of antibiotic resistance and the prevalence of opportunistic pathogens. [Display omitted] •13 antibiotics were detected in feed and 16 antibiotics in mariculture systems.•Sulfonamides resistance genes sul1 and sul2 were predominant in water and sediment.•Tetracycline resistance genes were prevalent in fish gill and gut.•Vibrio was significantly correlated with antibiotic resistance genes (ARGs).•Mariculture system is a reservoir of ARGs.