Details

Autor(en) / Beteiligte

• Zhang, Yun-Hong
• Shao, Zhu-Tao
• Bi, Guang-Ming
• Sun, Yi-Wei
• Wang, Yu-Meng
• Meng, Da-Li

Titel

Chemical constituents and biological activities of Artemisia argyi H.Lév. & vaniot

Ist Teil von

• Natural product research, 2023-04, Vol.37 (8), p.1401-1405

Ort / Verlag

England: Taylor & Francis Ltd

Erscheinungsjahr

2023

Quelle

Taylor & Francis

Beschreibungen/Notizen

• is a widely distributed and inexpensive plant resource, and study on its chemical compositions and biological activities will provide an important basis for its food applications and pharmaceutical developments. In this study, fourteen known guaiane-type sesquiterpenes (1-14), four known eudesmane-type sesquiterpenes (15-18), two known germacranolide-type sesquiterpenes (19, 20), and eight other types of terpenoids (20-28) were isolated from the leaves of by polyamide and ODS CC and HPLC. The structures of all compounds are determined by 1 D NMR ( H-NMR、 C-NMR) and literature comparison. Among them, compounds and were isolated from Chinese folk medicine for the first time. Besides, the LPS-induced RAW264.7 cell model has been evaluated the anti-inflammatory activities by the Griess reagent. The results indicated that the guaianolide sesquiterpenoids obtained from have an excellent ability to inhibit NO production, especially Argyin A, a guaianolide sesquiterpenoid with isovaleryloxy substitution.