Developmental cell, 2021-11, Vol.56 (22), p.3035-3037
2021
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- Autor(en) / Beteiligte
- Titel
- Two sides of the Dlk1-Dio3 story in imprinting
- Ist Teil von
- Developmental cell, 2021-11, Vol.56 (22), p.3035-3037
- Ort / Verlag
- United States
- Erscheinungsjahr
- 2021
- Quelle
- Free E-Journal (出版社公開部分のみ）
- Beschreibungen/Notizen
- Loss of imprinting (LOI) at the Dlk1-Dio3 locus is linked to Kagami-Ogata and Temple syndromes, and to cancer, but molecular mechanisms that prevent LOI are under-studied. In this issue of Developmental Cell, Aronson et al. demarcate the bipartite regulation of the Dlk1-Dio3 imprinting control region (ICR) IG-DMR, which maintains locus imprinting.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1534-5807eISSN: 1878-1551DOI: 10.1016/j.devcel.2021.10.021Titel-ID: cdi_proquest_miscellaneous_2601985380
- Format
- –
- Schlagworte
- Calcium-Binding Proteins - genetics, DNA Methylation, Genomic Imprinting, Humans, Membrane Proteins - genetics, Neoplasms