Details

Autor(en) / Beteiligte

• Yi, Ming-Jun
• Xiao, Teng-Fei
• Li, Wen-Hui
• Zhang, Yi-Fan
• Yan, Pen-Ji
• Zhang, Baoxin
• Xu, Peng-Fei
• Xu, Guo-Qiang

Titel

Organic photoredox catalytic α-C(sp 3 )-H phosphorylation of saturated aza -heterocycles

Ist Teil von

• Chemical communications (Cambridge, England), 2021-12, Vol.57 (97), p.13158-13161

Ort / Verlag

England: Royal Society of Chemistry

Erscheinungsjahr

2021

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A metal-free C(sp )-H phosphorylation of saturated -heterocycles the merger of organic photoredox and Brønsted acid catalyses was established under mild conditions. This protocol provided straightforward and economic access to a variety of valuable α-phosphoryl cyclic amines by using commercially available diarylphosphine oxide reagents. In addition, the D-A fluorescent molecule DCQ was used for the first time as a photocatalyst and exhibited an excellent photoredox catalytic efficiency in this transformation. A series of mechanistic experiments and DFT calculations demonstrated that this transformation underwent a sequential visible light photoredox catalytic oxidation/nucleophilic addition process.