The New England journal of medicine, 2021-08, Vol.385 (8), p.695-706
2021
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Details
- Autor(en) / Beteiligte
- Titel
- Atogepant for the Preventive Treatment of Migraine
- Ist Teil von
- The New England journal of medicine, 2021-08, Vol.385 (8), p.695-706
- Ort / Verlag
- United States: Massachusetts Medical Society
- Erscheinungsjahr
- 2021
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Daily use of atogepant (a small-molecule, calcitonin gene–related peptide receptor antagonist) at any of three doses resulted in greater reductions in migraine days per month over a period of 12 weeks than did placebo. Nausea and constipation were side effects in approximately 5% of the participants who received atogepant.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0028-4793eISSN: 1533-4406DOI: 10.1056/NEJMoa2035908Titel-ID: cdi_proquest_miscellaneous_2562831805
- Format
- –
- Schlagworte
- Adolescent, Adult, Adverse events, Aged, Asthma, Calcitonin, Calcitonin Gene-Related Peptide Receptor Antagonists - administration & dosage, Calcitonin Gene-Related Peptide Receptor Antagonists - adverse effects, Calcitonin Gene-Related Peptide Receptor Antagonists - therapeutic use, Clinical Practice, Constipation, Constipation - chemically induced, COVID-19, Diaries, Dose-Response Relationship, Drug, Double-Blind Method, Drugs, Female, Headache, Headaches, Hospitalist, Humans, Intention to Treat Analysis, Male, Middle Aged, Migraine, Migraine Disorders - prevention & control, Monoclonal antibodies, Narcotics, Nausea, Nausea - chemically induced, Neuritis, Neurology, Neurosurgery, Neurosurgery General, Optic neuritis, Piperidines - administration & dosage, Piperidines - adverse effects, Piperidines - therapeutic use, Placebos, Prevention, Primary Care, Pyridines - administration & dosage, Pyridines - adverse effects, Pyridines - therapeutic use, Pyrroles - administration & dosage, Pyrroles - adverse effects, Pyrroles - therapeutic use, Quality of life, Questionnaires, Regulatory approval, Spiro Compounds - administration & dosage, Spiro Compounds - adverse effects, Spiro Compounds - therapeutic use, Young Adult