Details

Autor(en) / Beteiligte

• Hevilla, Víctor
• Sonseca, Agueda
• Echeverría, Coro
• Muñoz‐Bonilla, Alexandra
• Fernández‐García, Marta

Titel

Enzymatic Synthesis of Polyesters and Their Bioapplications: Recent Advances and Perspectives

Ist Teil von

• Macromolecular bioscience, 2021-10, Vol.21 (10), p.e2100156-n/a

Ort / Verlag

Germany: Wiley Subscription Services, Inc

Erscheinungsjahr

2021

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• This article reviews the most important advances in the enzymatic synthesis of polyesters. In first place, the different processes of polyester enzymatic synthesis, i.e., polycondensation, ring opening, and chemoenzymatic polymerizations, and the key parameters affecting these reactions, such as enzyme, concentration, solvent, or temperature, are analyzed. Then, the latest articles on the preparation of polyesters either by direct synthesis or via modification are commented. Finally, the main bioapplications of enzymatically obtained polyesters, i.e., antimicrobial, drug delivery, or tissue engineering, are described. It is intended to point out the great advantages that enzymatic polymerization present to obtain polymers and the disadvantages found to develop applied materials. This article reviews recent studies in the development of polyesters obtained via enzymatic synthesis and their possible applications in the field of biomedicine, such as in scaffolds, drug delivery, gene therapy, or antimicrobial systems.