Details

Autor(en) / Beteiligte

• Ferreira, João Pedro Sousa
• de Mascarenhas Saraiva, Miguel José da Quinta e Costa
• Afonso, João Pedro Lima
• Ribeiro, Tiago Filipe Carneiro
• Cardoso, Hélder Manuel Casal
• Ribeiro Andrade, Ana Patrícia
• de Mascarenhas Saraiva, Miguel Nuno Gameiro
• Parente, Marco Paulo Lages
• Natal Jorge, Renato
• Lopes, Susana Isabel Oliveira
• de Macedo, Guilherme Manuel Gonçalves

Titel

Identification of Ulcers and Erosions by the Novel Pillcam™ Crohn’s Capsule Using a Convolutional Neural Network: A Multicentre Pilot Study

Ist Teil von

• Journal of Crohn's and colitis, 2022-01, Vol.16 (1), p.169-172

Ort / Verlag

UK: Oxford University Press

Erscheinungsjahr

2022

Quelle

Oxford Journals 2020 Medicine

Beschreibungen/Notizen

• Abstract Background and Aims Capsule endoscopy is a central element in the management of patients with suspected or known Crohn’s disease. In 2017, PillCam™ Crohn’s Capsule was introduced and demonstrated to have greater accuracy in the evaluation of extension of disease in these patients. Artificial intelligence [AI] is expected to enhance the diagnostic accuracy of capsule endoscopy. This study aimed to develop an AI algorithm for the automatic detection of ulcers and erosions of the small intestine and colon in PillCam™ Crohn’s Capsule images. Methods A total of 8085 PillCam™ Crohn’s Capsule images were extracted between 2017 and 2020, comprising 2855 images of ulcers and 1975 erosions; the remaining images showed normal enteric and colonic mucosa. This pool of images was subsequently split into training and validation datasets. The performance of the network was subsequently assessed in an independent test set. Results The model had an overall sensitivity and specificity of 90.0% and 96.0%, respectively. The precision and accuracy of this model were 97.1% and 92.4%, respectively. In particular, the algorithm detected ulcers with a sensitivity of 83% and specificity of 98%, and erosions with sensitivity and specificity of 91% and 93%, respectively. Conclusion A deep learning model capable of automatically detecting ulcers and erosions in PillCam™ Crohn’s Capsule images was developed for the first time. These findings pave the way for the development of automatic systems for detection of clinically significant lesions, optimizing the diagnostic performance and efficiency of monitoring Crohn’s disease activity.