Details

Autor(en) / Beteiligte

• Keszthelyi, Daniel

Titel

Irritable Bowel Syndrome and Functional Dyspepsia: Different Ends of the Same Spectrum of Intestinal Barrier Dysfunction?

Ist Teil von

• The American journal of gastroenterology, 2021-07, Vol.116 (7), p.1556-1556

Ort / Verlag

New York: Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins

Erscheinungsjahr

2021

Beschreibungen/Notizen

• Small intestinal barrier function has also received considerable attention as a potential pathomechanisms in irritable bowel syndrome (IBS) (2), and this in fact predates similar hypotheses with regards to FD. Evidence of duodenal epithelial barrier impairment and increased pyroptosis in patients with functional dyspepsia on confocal laser endomicroscopy and ex vivo mucosa analysis. Increased gaps in the intestinal epithelium of irritable bowel syndrome patients identified by confocal laser endomicroscopy (with videos).