Details

Autor(en) / Beteiligte

• Hu, Xing-Rong
• Zhou, Ming-Wang
• Liu, Hai-Ping
• Li, Sheng-Hua
• Chen, Yan-Tong
• Liu, Yi-Fei
• Wang, Peng-Zhi
• Zhao, Qiu-Yue
• Xiao, Zhen

Titel

Expression of Ras-Associated Protein 1 in the Vascular Endothelium of Bone Tissue with Non-Traumatic Osteonecrosis of Femoral Head

Ist Teil von

• Sichuan da xue xue bao. Journal of Sichuan University. Yi xue ban, 2021-05, Vol.52 (3), p.452-457

Ort / Verlag

China

Erscheinungsjahr

2021

Quelle

MEDLINE

Beschreibungen/Notizen

• To investigate the difference in the expression of Ras-associated protein 1 (Rap1) in necrotic and healthy areas of non-traumatic osteonecrosis of femoral head (NONFH) patients. Femoral head tissue samples from 30 cases of NONFH and 30 cases of traumatic osteonecrosis of the femoral head (TONFH) were collected after hip replacement surgery, respectively. No significant difference of Association Research Circulation Osseous (ARCO) staging was found between the NONFH and the TONFH groups ( =-0.769, =0.442). In the NONFH group, 8 patients were ARCO stage IIIb, 10 were stage IV, and 12 were stage V, while in the TONFH ground, 11 patients were ARCO stage IIIb, 9 were stage IV, and 10 were stage V. There were 19 males and 11 females in the NONFH group, with an average age of 49.6 yr. (26-69 yr.), and 16 males and 14 females in the TONFH group, with an average age of 54.2 yr. (37-68 yr.). There was no significant difference in gender or age between the two groups ( >0.05). Specimens were collected from different bon