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Childhood viral infections may be beneficial to cognition in old age
Ist Teil von
International psychogeriatrics, 2021-01, Vol.33 (1), p.19-20
Ort / Verlag
Cambridge, UK: Cambridge University Press
Erscheinungsjahr
2021
Link zum Volltext
Quelle
Applied Social Sciences Index & Abstracts (ASSIA)
Beschreibungen/Notizen
Cognitive functionings, non-pathological age-related cognitive changes, and the risk of dementia can be influenced by the developmental environment, health, and lifestyle over the life span as well as heritable factors. In general, viruses result in an imbalance in the cellular redox environment, which depending on the virus and the cell could result in multiple responses (e.g. antioxidant defenses) that can be the common final pathway behind the hormesis mechanism (Camini et al., 2017). Griffin and Mark propose that a paucity of exposure to environmental pathogens retards proper immune system development, and consequently decreases its ability to effectively thwart a variety of effectors with degenerative consequences, such as those associated with chronic inflammatory responses in diseases as seemingly diverse as those of the brain (Rook, 2010).