Details

Autor(en) / Beteiligte

• Yang, Qi-Liang
• Jia, Hong-Wei
• Liu, Ying
• Xing, Yi-Kang
• Ma, Rui-Cong
• Wang, Man-Man
• Qu, Gui-Rong
• Mei, Tian-Sheng
• Guo, Hai-Ming

Titel

Electrooxidative Iridium-Catalyzed Regioselective Annulation of Benzoic Acids with Internal Alkynes

Ist Teil von

• Organic letters, 2021-02, Vol.23 (4), p.1209-1215

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2021

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Electrochemically driven, Cp*Ir­(III)-catalyzed regioselective annulative couplings of benzoic acids with alkynes have been established herein. The combination of iridium catalyst and electricity not only circumvents the need for stoichiometric amount of chemical oxidant, but also ensures broad reaction compatibility with a wide array of sterically and electronically diverse substrates. This electrochemical approach represents a sustainable strategy as an ideal alternative and supplement to the oxidative annulations methodology to be engaged in the synthesis of isocoumarin derivatives.