Details

Autor(en) / Beteiligte

• Sud, Sachin
• Friedrich, Jan O.
• Adhikari, Neill K. J.
• Fan, Eddy
• Ferguson, Niall D.
• Guyatt, Gordon
• Meade, Maureen O.

Titel

Comparative Effectiveness of Protective Ventilation Strategies for Moderate and Severe Acute Respiratory Distress Syndrome. A Network Meta-Analysis

Ist Teil von

• American journal of respiratory and critical care medicine, 2021-06, Vol.203 (11), p.1366-1377

Ort / Verlag

New York: American Thoracic Society

Erscheinungsjahr

2021

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Sud et al. discuss the comparative effectiveness of protective ventilation strategies for moderate and severe acute respiratory distress syndrome. The authors performed a network meta-analysis of randomized trials. They analyzed 34 trials including 9,085 adults with primarily moderate-to-severe ARDS (median baseline PaO2/FiO2, 118; interquartile range, 110-143). Their findings suggest that combining low Vt with prone ventilation is associated with the greatest reduction in mortality for critically ill adults with moderate-to-severe ARDS.