Details

Autor(en) / Beteiligte

• Gawlik, N.R.
• Makrides, M.
• Kettler, L.
• Yelland, L.N.
• Leemaqz, S.
• Gould, J.F.

Titel

The influence of DHA supplementation during pregnancy on language development across childhood: Follow-up of a randomised controlled trial

Ist Teil von

• Prostaglandins, leukotrienes and essential fatty acids, 2020-12, Vol.163, p.102207-102207, Article 102207

Ort / Verlag

Scotland: Elsevier Ltd

Erscheinungsjahr

2020

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• •We explored language development across childhood after prenatal DHA supplementation.•Multiple domains of language were assessed and compared at 1.5, 4 and 7 years of age.•Prenatal DHA supplementation does not enhance the development of child language abilities. Numerous randomised controlled trials have explored the effect of docosahexaenoic acid (DHA) supplementation in early life on neurodevelopment, with some suggested positive effects on language. Australian women with a singleton pregnancy <21 weeks’ gestation were randomised to receive 800 mg DHA/day or a placebo until birth. A sample of 726 children (all n=96 born preterm, random sample of n=630 born at term) were invited to undergo assessments of language, academic, and language-based cognitive abilities at 1.5, four and seven years of age. No group differences were detected for any group comparison. Exploratory analyses for sex by treatment interactions revealed a possible adverse effect of DHA supplementation on the language of females at 1.5 years but no effects on outcomes at four or seven years. Taken as a whole, evidence of an effect of prenatal DHA supplementation on language abilities across childhood is negligible and could be a chance finding.