Details

Autor(en) / Beteiligte

• Lee, Boram
• Han, Ho‐Seong
• Yoon, Yoo‐Seok
• Cho, Jai Young
• Lee, Jun Suh

Titel

Impact of preoperative malnutrition, based on albumin level and body mass index, on operative outcomes in patients with pancreatic head cancer

Ist Teil von

• Journal of hepato-biliary-pancreatic sciences, 2021-12, Vol.28 (12), p.1069-1075

Ort / Verlag

Japan: Wiley Subscription Services, Inc

Erscheinungsjahr

2021

Link zum Volltext

Quelle

Wiley Online Library - AutoHoldings Journals

Beschreibungen/Notizen

• Background To investigate whether preoperative malnutrition in patients who underwent curative pancreaticoduodenectomy (PD) in pancreatic head cancer correlated with short‐term outcomes. Methods This study was a retrospective review of medical records from January 2004 to December 2018. Preoperative malnutrition was defined as body mass index (BMI) <18.5 kg/m2, or hypoalbuminemia with serum albumin level < 3.5 g/dL within 30 days before surgery. Results Of the 289 eligible patients, 60 patients (20.7%) were classified as the malnutrition group. The estimated blood loss (EBL, mL) (964.1 ± 879.7 vs 597.7 ± 501.7, P = .044) and transfusion rate (51.7% vs 18.8%, P < .001) was significantly higher in the malnutrition group than no‐malnutrition group. The hospital stay (days) (20.5 ± 12.2 vs 18.1 ± 13.6, P = .05) was significantly longer in the malnutrition group. The open conversion rate (45.4% vs 6.67%, P < .001) and major complication rate (36.7% vs 21.8%, P = .032) was significantly higher in the malnutrition group. In multivariate analysis, preoperative malnutrition was found to be the predictor of postoperative complication (HR 1.971 95% confidence interval 1.071‐3.624, P = .029). Conclusion Preoperative malnutrition in patients who underwent curative PD for pancreatic head cancer is associated with adverse short‐term outcomes. Highlight No study has been reported on the association between preoperative malnutrition and surgical outcomes in pancreatic cancer. Among patients who underwent curative pancreaticoduodenectomy, Lee and colleagues revealed that those with preoperative malnutrition had increased blood loss, open conversion rates, hospital stay, and complication rates compared with those without preoperative malnutrition.