Details

Autor(en) / Beteiligte

• Goh, Winfred Xi Tai
• Too, Chow Wei
• Lee, Kristen Alexa
• Tan, Bien Soo
• Tay, Kiang Hiong
• Chandramohan, Sivanathan
• Lo, Richard Hoau Gong
• Irani, Farah Gillan
• Venkatanarasimha, Nanda
• Damodharan, Karthikeyan
• Kumar, Kutty Krishnan Pradesh
• Zhuang, Kun Da
• Chua, Jasmine Ming Er
• Bangaragiri, Ajay
• Leong, Sum

Titel

Management of arterial dissections in 12 patients during transarterial chemoembolization and yttrium-90 selective internal radiotherapy for primary and secondary liver tumours

Ist Teil von

• Abdominal radiology (New York), 2021-04, Vol.46 (4), p.1737-1745

Ort / Verlag

New York: Springer US

Erscheinungsjahr

2021

Link zum Volltext

Quelle

SpringerLink (Online service)

Beschreibungen/Notizen

• Objective To describe rates and management strategies of arterial dissections in transarterial chemoembolization (TACE) and Yttrium-90 selective internal radiotherapy ( 90 Y SIRT) for primary and secondary liver tumours. Materials and methods This retrospective review included 1377 hepatic angiographies between May 2010 and June 2015 in a single centre for TACE and 90 Y SIRT of liver tumours. The angiogram results, management, treatment outcomes and follow-up angiography/imaging findings were recorded. Results and discussion Twelve cases of arterial dissections (12/1377, 0.87%) were documented. Three dissections (3/633, 0.47%) occurred during TACE, seven (7/449, 1.56%) during pre-treatment planning angiographies (PTPA) for 90 Y SIRT, and two (2/249, 0.80%) during the treatment procedure of 90 Y SIRT. The preferred management strategy was to manoeuvre past the dissection and complete the procedure, which was achieved in six patients (50%). Angioplasty with stenting was performed in one patient. In three patients, the procedure was held off for up to 3 months to allow the dissection to heal before repeating the procedure. A dissection that occurred during PTPA was detected only when the patient returned for 90 Y SIRT. PTPA was immediately repeated for this patient. The last patient opted for sorafenib. Residual 50% stenosis was seen in one patient on follow-up hepatic angiography, but he was otherwise asymptomatic. In the remaining patients, no residual dissection or clinical sequelae was observed on follow-up. Conclusion Arterial dissection is a rare but important complication of transarterial locoregional therapy. Where possible, attempts should be made at completing the therapy. Deferring treatment can be considered as dissections usually heal within 3 months. Level of evidence Level 4, case series.