Details

Autor(en) / Beteiligte

• Held, Laura
• Ruetten, Arno
• Saggini, Andrea
• Kempter, Wolfgang
• Tiedke, Carmen
• Weber‐Kuhn, Susanne
• De Saint Aubain, Nicolas
• Mentzel, Thomas

Titel

Metaplastic spiradenocarcinoma: Report of two cases with sarcomatous differentiation

Ist Teil von

• Journal of cutaneous pathology, 2021-03, Vol.48 (3), p.384-389

Ort / Verlag

Oxford, UK: Blackwell Publishing Ltd

Erscheinungsjahr

2021

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• Spiradenocarcinoma (SC) is a very rare malignant skin adnexal tumor with sweat gland differentiation that develops from a pre‐existing spiradenoma, cylindroma, or hybrid tumor called spiradenocylindroma, or arises de novo. We present two exceptionally rare SC cases showing sarcomatous differentiation; we also discuss the clinicopathologic features of SC, as well as its differential diagnoses and available therapeutic modalities. Given the aggressive behavior of SC, rapid diagnosis and complete removal of the tumor with tumor‐free margins is mandatory. Owing to the marked morphological heterogeneity of individual SC cases, dermatopathologists must be familiar with the different possible histopathologic manifestations of this neoplasm.