Details

Autor(en) / Beteiligte

• Nakaya, Aya
• Kohara, Takae
• Shibayama, Hirohiko
• Onda, Yoshiyuki
• Kanda, Junya
• Kaneko, Hitomi
• Imada, Kazunori
• Kida, Toru
• Kosugi, Satoru
• Ishikawa, Jun
• Yamamura, Ryosuke
• Shimazu, Yutaka
• Tanaka, Hirokazu
• Fuchida, Shin-ichi
• Shimura, Yuji
• Kiyota, Miki
• Wada, Katsuya
• Ito, Tomoki
• Uoshima, Nobuhiko
• Yagi, Hideo
• Yoshihara, Satoshi
• Ohta, Kensuke
• Shimazaki, Chihiro
• Hino, Masayuki
• Takaori-Kondo, Akifumi
• Kuroda, Junya
• Matsumura, Itaru
• Kanakura, Yuzuru
• Nomura, Shosaku

Titel

Retrospective multi-center study of Adolescent and Young Adult (AYA) Multiple Myeloma in Kansai Myeloma Forum registry

Ist Teil von

• International journal of hematology, 2020-10, Vol.112 (4), p.435-438

Ort / Verlag

Singapore: Springer Singapore

Erscheinungsjahr

2020

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• We retrospectively analyzed the clinical features and outcomes in a real-world cohort of adolescents and the young adult (AYA) patients (age between 16 and 39 years) with symptomatic multiple myeloma (MM) registered with the Kansai Myeloma Forum. 26 patients had been diagnosed as symptomatic MM out of 3284 patients. The prevalence of AYA-MM was 0.8% in this cohort. 81% of the patients was received stem cell transplantation, which may improve outcome. Anemia and hypercalcemia might be prognostic factors, however International Staging System failed to predict overall survival. Five patients developed late-onset adverse events which were serious and life-threatening. The 5-year overall survival was 71.0%. We need to develop the new strategy to overcome AYA-MM.