Details

Autor(en) / Beteiligte

• Agnello, Francesco
• Albano, Domenico
• Sparacia, Gianvincenzo
• Micci, Giuseppe
• Matranga, Domenica
• Toia, Patrizia
• La Grutta, Ludovico
• Grassedonio, Emanuele
• Lo Re, Giuseppe
• Salvaggio, Giuseppe
• Midiri, Massimo
• Galia, Massimo

Titel

Outcome of LR-3 and LR-4 observations without arterial phase hyperenhancement at Gd-EOB-DTPA-enhanced MRI follow-up

Ist Teil von

• Clinical imaging, 2020-12, Vol.68, p.169-174

Ort / Verlag

Philadelphia: Elsevier Inc

Erscheinungsjahr

2020

Link zum Volltext

Quelle

ScienceDirect

Beschreibungen/Notizen

• The aim of this study was to retrospectively analyze the outcome of LR-3 and LR-4 without arterial phase hyperenhancement (APHE), and identify which features could predict LR-5 progression on serial Gd-EOB-DTPA-enhanced MRI follow-up. Forty-nine cirrhotic patients with 55 LR-3 and 19 LR-4 without APHE were evaluated. Observations were classified as decreased, stable or increased in category at follow-up. Observation size and LI-RADS major and ancillary features were evaluated. Seventeen/fifty-five (31%) LR-3 and 8/19 (42%) LR-4 progressed to LR-5 at follow-up. Baseline LI-RADS major and ancillary features were not significantly different among LR-3 and LR-4. A diameter ≥ 10 mm significantly increased LR-5 progression risk of LR-3 (OR = 6.07; 95% CI: 0.12; 60.28]; P < .001). LR-4 with a diameter ≥ 10 mm more likely become LR-5 at follow-up (OR = 8.95; 95% CI: 0.73; 111.8; P = .083]). LR-3 and LR-4 without APHE were often downgraded or remained stable in category on Gd-EOB-DTPA-enhanced MRI follow-up. •Most LR-3 and LR-4 without APHE were downgraded or remained stable in category on Gd-EOB-DTPA-enhanced MRI follow-up.•Baseline major and ancillary Li-RADS features were not significantly different between observations that progressed from LR-3 and LR-4 to LR-5 and those that did not.•Diameter of at least one 10 mm increased the risk of LR-5 transformation of LR-3 and LR-4.