Details

Autor(en) / Beteiligte

• Pang, Zhiqian
• Zhang, Li
• Coaker, Gitta
• Ma, Wenbo
• He, Sheng-Yang
• Wang, Nian

Titel

Citrus CsACD2 Is a Target of Candidatus Liberibacter Asiaticus in Huanglongbing Disease

Ist Teil von

• Plant physiology (Bethesda), 2020-10, Vol.184 (2), p.792-805

Ort / Verlag

United States

Erscheinungsjahr

2020

Quelle

MEDLINE

Beschreibungen/Notizen

• Citrus Huanglongbing (HLB), caused by Liberibacter asiaticus (Las), is one of the most destructive citrus diseases worldwide, yet how Las causes HLB is poorly understood. Here we show that a Las-secreted protein, SDE15 (CLIBASIA_04025), suppresses plant immunity and promotes Las multiplication. Transgenic expression of SDE15 in Duncan grapefruit ( ) suppresses the hypersensitive response induced by ssp. ( ) and reduces the expression of immunity-related genes. SDE15 also suppresses the hypersensitive response triggered by the effector protein AvrBsT in , suggesting that it may be a broad-spectrum suppressor of plant immunity. SDE15 interacts with the citrus protein CsACD2, a homolog of Arabidopsis ( ) ACCELERATED CELL DEATH 2 (ACD2). SDE15 suppression of plant immunity is dependent on , and overexpression of in citrus suppresses plant immunity and promotes Las multiplication, phenocopying overexpression of SDE15. Identification of CsACD2 as a susceptibility target has implications in genome editing for novel plant resistance against devastating HLB.