Details

Autor(en) / Beteiligte

• Rajabkhah, Sahebeh
• Moradi, Kamyar
• Okhovat, Ali A.
• Van Alfen, Nens
• Fathi, Davood
• Aghaghazvini, Leila
• Ashraf‐Ganjouei, Amir
• Attarian, Shahram
• Nafissi, Shahriar
• Fatehi, Farzad

Titel

Application of muscle ultrasound for the evaluation of patients with amyotrophic lateral sclerosis: An observational cross‐sectional study

Ist Teil von

• Muscle & nerve, 2020-10, Vol.62 (4), p.516-521

Ort / Verlag

Hoboken, USA: John Wiley & Sons, Inc

Erscheinungsjahr

2020

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• Introduction We evaluated the association between muscle ultrasound, number of motor units, and clinical parameters, and assessed their utility for distinguishing amyotrophic lateral scleorisis (ALS) patients from healthy individuals. Methods Three muscle pairs (abductor pollicis brevis, abductor digiti minimi, and tibialis anterior) of 18 ALS patients and 18 controls underwent muscle ultrasound (echointensity and thickness) and assessment of motor unit number index (MUNIX). The clinical and functional status of participants were also assessed. Results Mean age of the patients was 53.8 ± 12.1 years, and score on the ALS Functional Rating Scale—Revised was 38.9 ± 4.1. Echointensity of all tested muscles of ALS participants was significantly higher than that of controls, but there was no significant difference in muscle thickness. Muscle echointensity correlated significantly with clinical and electrophysiological parameters. Conclusion Echointensity of muscles was highly associated with clinical scales and MUNIX, confirming its relevance as an ancillary diagnostic test in ALS patients.