Details

Autor(en) / Beteiligte

• Li, Xingzhe
• Lee, Anna
• Cohen, Marc A.
• Sherman, Eric J.
• Lee, Nancy Y.

Titel

Past, present and future of proton therapy for head and neck cancer

Ist Teil von

• Oral oncology, 2020-11, Vol.110, p.104879-104879, Article 104879

Ort / Verlag

Elsevier Ltd

Erscheinungsjahr

2020

Quelle

Access via ScienceDirect (Elsevier)

Beschreibungen/Notizen

• •Proton therapy has been increasingly used in head and neck cancer treatment in recent decades.•Proton therapy minimizes dose to critical organs, decreases toxicities and improves outcomes.•Proton therapy will see wider adoption with clinical, technological and biological advances. Proton therapy has recently gained substantial momentum worldwide due to improved accessibility to the technology and sustained interests in its advantage of better tissue sparing compared to traditional photon radiation. Proton therapy in head and neck cancer has a unique advantage given the complex anatomy and proximity of targets to vital organs. As head and neck cancer patients are living longer due to epidemiological shifts and advances in treatment options, long-term toxicity from radiation treatment has become a major concern that may be better mitigated by proton therapy. With increased utilization of proton therapy, new proton centers breaking ground, and as excitement about the technology continue to increase, we aim to comprehensively review the evidence of proton therapy in major subsites within the head and neck, hoping to facilitate a greater understanding of the full risks and benefits of proton therapy for head and neck cancer.