Details

Autor(en) / Beteiligte

• Garcia-Estrada, Christian
• Casallas-Vanegas, Adriana
• Zabala-Angeles, Indhira
• Gomez-Figueroa, Enrique
• Rivas-Alonso, Verónica
• Flores-Rivera, José

Titel

Rituximab as an effective therapeutic option in refractory Neuro-Behçet syndrome

Ist Teil von

• Journal of neuroimmunology, 2020-09, Vol.346, p.577308-577308, Article 577308

Ort / Verlag

Netherlands: Elsevier B.V

Erscheinungsjahr

2020

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Behçet's disease (BD) is an inflammatory disease of unknown etiology with periods of relapses and remissions. Neuro-Behçet syndrome (NBS) is one of the main causes of long-term morbidity and mortality, making its prompt recognition and early treatment fundamental to achieving a better outcome. Currently there are no treatment guidelines either for BS or NB, making the management of these patients particularly difficult. We present the case report of a patient with pseudo-tumoral lesion and myelitis refractory to steroids and cyclophosphamide who successfully showed remission after treatment with an anti-CD20 therapy. This is the first report of concomitant pseudo-tumoral lesion and myelitis secondary to BS. We found rituximab treatment to be a safe and effective therapeutic option for NB supported by the radiological and clinical improvement achieved in our patient. [Display omitted]