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Advances in upstream and downstream strategies of pectinase bioprocessing: A review
Ist Teil von
International journal of biological macromolecules, 2020-11, Vol.162, p.1086-1099
Ort / Verlag
Netherlands: Elsevier B.V
Erscheinungsjahr
2020
Quelle
MEDLINE
Beschreibungen/Notizen
This review aims to highlight the bioprocessing strategies behind one of the most commercially produced enzymes in the biotechnological market, pectinase. Significant steps in the upstream processing of this enzyme include its source, the selection of the substrate, the reaction conditions and the overall reactor design, all of which will be discussed in great detail. Past literature which has contributed to the viability of this design will be highlighted with the intention of generating a comparative review that accounts not only for the contributions of previous research but also for what needs to be done in the future to further increase the productivity of this vital industrial process. There is an incredibly wide net of application based research and industry which currently depends on the bioprocessing of pectinase, these will thereby benefit greatly from the concepts of process intensification and optimisation which are at the forefront of this review and will likely be inspired by the outlined steps that need to be taken to further improve this process.