Details

Autor(en) / Beteiligte

• Ortiz-Díez, Gustavo
• López, Raúl
• Sánchez-Díaz, Ana María
• Turrientes, María-Carmen
• Baquero, María-Rosario
• Luque, Ruth
• Maroto, Alba
• Fernández, Cristina
• Ayllón, Tania

Titel

Epidemiology of the colonization and acquisition of methicillin-resistant staphylococci and vancomycin-resistant enterococci in dogs hospitalized in a clinic veterinary hospital in Spain

Ist Teil von

• Comparative immunology, microbiology and infectious diseases, 2020-10, Vol.72, p.101501-101501, Article 101501

Ort / Verlag

England: Elsevier Ltd

Erscheinungsjahr

2020

Quelle

MEDLINE

Beschreibungen/Notizen

• •Multiresistant bacteria represent a potential risk of transmission to humans from infected or colonized companion animals.•Prevalence, incidence and risk factors for the acquisition and persistence of MRS and VRE was estimated in hospitalized canine patients in Madrid, Spain.•A prevalence of 13.9% and incidence of 26.5% of dogs colonized by MRS was observed at hospital admission and release. VRE was not isolated from any dog.•Several risk factors were associated with MRS colonization at hospital admission and during hospitalization.•Identification of resistance problems, early sampling in risk groups and the responsible use of antimicrobials should be urgently implemented to mitigate the risk of MRS infection in dogs. Antibiotic resistance is one of the biggest threats to human and animal health. Methicillin-resistant Staphylococcus spp. (MRS) and vancomycin-resistant Enterococcus spp. (VRE) are of increasing importance in hospital and/or nosocomial infections and represent a potential risk of transmission to humans from infected or colonized companion animals. Studies on the risk factors associated with colonization by multiresistant bacteria in animals are scarce. The present study aimed to estimate the prevalence and incidence of MRS and VRE in canine patients hospitalized in a veterinary hospital and to identify the risk factors for its acquisition and persistence. Nasal and perianal swabs were obtained from 72 dogs. Antimicrobial susceptibility assays and molecular detection of mecA and van genes were performed. A prevalence of 13.9% and incidence of 26.5% was observed in dogs colonized by MRS at hospital admission and release, respectively, higher values than those described in most veterinary studies. Thirty-five Staphylococcus isolates had mecA gene and showed higher resistance levels to most of the antimicrobials evaluated. Previous and concomitant use of antibiotics and corticosteroids has been associated with an increase in MRS colonization. The use of antibiotics in other animals living with the canine patients has also been identified as an associated factor, suggesting cross transmission. The presence of van-resistant genes from Enterococcus spp. was not detected. Pets should be considered possible vehicles of transmission and reservoirs for MRS bacteria and veterinary hospitals should be considered high-risk environments for the occurrence and spread of nosocomial infections and resistant bacteria.