Details

Autor(en) / Beteiligte

• Brainin, Michael
• Feigin, Valery L
• Norrving, Bo
• Martins, Sheila Cristina Ouriques
• Hankey, Graeme J
• Hachinski, Vladimir

Titel

Global prevention of stroke and dementia: the WSO Declaration

Ist Teil von

• Lancet neurology, 2020-06, Vol.19 (6), p.487-488

Ort / Verlag

England: Elsevier Ltd

Erscheinungsjahr

2020

Quelle

Elsevier ScienceDirect Journals Complete

Beschreibungen/Notizen

• [...]a motivational population-wide strategy using the free Stroke Riskometer app to reduce lifestyle and other risk factors in adults at any increased risk of stroke development. [...]a polypill strategy (consisting of two generic low-dose blood pressure drugs [eg, losartan 16 mg and amlodipine 2·5 mg] and one generic lipid lowering medication [eg, rosuvastatin calcium 10 mg]) for middle-age and older adults at risk of cardiovascular disease (ie, those with at least two behavioural or metabolic cardiovascular disease risk factors). [...]it excludes people with low-to-moderate cardiovascular disease risk who will ultimately comprise about 80% of future strokes and cardiovascular events, and thereby might have been falsely reassured that they are protected from developing these diseases. [...]evidence is lacking for the effectiveness of the high-risk approach in preventing stroke and acute cardiovascular events at the population level (appendix p1).