Details

Autor(en) / Beteiligte

• Fritz-Laylin, Lillian K.

Titel

The evolution of animal cell motility

Ist Teil von

• Current biology, 2020-05, Vol.30 (10), p.R477-R482

Ort / Verlag

England: Elsevier Inc

Erscheinungsjahr

2020

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Eukaryotic cells use a number of diverse mechanisms to swim through liquid or crawl across solid surfaces. The two most prevalent forms of eukaryotic cell motility are flagellar-dependent swimming and actin-dependent cell migration, both of which are used by animal cells and unicellular eukaryotes alike. Evolutionary cell biologists have used morphological and molecular phenotypes to trace the evolution of flagellar-based swimming. These efforts have resulted in a large body of evidence supporting a single evolutionary origin of the eukaryotic flagellum, an origin that dates back to before the diversification of modern eukaryotes. Actin-dependent crawling, in contrast, involves mutiple distinct molecular mechanisms, the evolution of which is just beginning to be explored. In this Essay, Fritz-Laylin discusses what we know — and what we don’t know — about the evolution of animal cell motility, with a particular focus on actin-dependent cell migration and flagellar motility.