Details

Autor(en) / Beteiligte

• Wu, Meng-yin
• Wang, Jian-bing
• Zhu, Yao
• Lu, Jie-ming
• Li, Die
• Yu, Zhe-bin
• Shen, Peng
• Jiang, Dan-jie
• Lin, Hong-bo
• Chen, Kun

Titel

Impact of Individual and Combined Lifestyle Factors on Mortality in China: A Cohort Study

Ist Teil von

• American journal of preventive medicine, 2020-09, Vol.59 (3), p.461-468

Ort / Verlag

Netherlands: Elsevier Inc

Erscheinungsjahr

2020

Link zum Volltext

Quelle

Applied Social Sciences Index & Abstracts (ASSIA)

Beschreibungen/Notizen

• Although numerous studies have suggested that lifestyle-related factors are associated with chronic diseases and preventable deaths, limited evidence is available for the Chinese population. This study established a prospective cohort of >360,000 residents on the basis of the Yinzhou Health Information System in China during 2004–2017 and calculated the combined effects of lifestyle-related factors, including BMI, smoking, alcohol consumption, and physical activity, using a points system. A Cox regression model estimated the combined effects of lifestyle-related factors on total mortality, and a competing risk model estimated the combined effects on cancer and cardiovascular disease mortality. All data analyses were conducted in 2018‒2019. During 3,755,879 person-years of follow-up, 11,791 deaths were identified, including 4,983 from cancer and 3,143 from cardiovascular disease. Having a standard BMI, never smoking, never drinking, and engaging in physical activity more than 4 times per week had protective effects on total mortality. Overall, the risk of total and cause-specific mortality increased with the increment of risk score. Compared with subjects in the lowest quartile, the risk of total and cause-specific mortality peaked among individuals in the fourth quartile (total mortality: hazard ratio=1.87, 95% CI=1.77, 1.98; cancer mortality: hazard ratio=2.05, 95% CI=1.87, 2.25; cardiovascular disease mortality: hazard ratio=1.51, 95% CI=1.35, 1.68). Sensitivity analyses excluding individuals with follow-up <3 years did not materially change the results. The combined effects of lifestyle-related factors, including BMI, smoking, alcohol drinking, and physical activity, are associated with total, cancer, and cardiovascular disease mortality among the Chinese population.