Details

Autor(en) / Beteiligte

• Kesim‐Sahin, Ozlem
• Sirin, Nermin Gorkem
• Erbas, Bahar
• Artug, Tugrul
• Oguz‐Akarsu, Emel
• Kocasoy‐Orhan, Elif
• Baslo, Mehmet Baris
• Mammadova, Nermin
• Emekli, Ufuk
• Oge, Ali Emre

Titel

Compound muscle action potential scan and MScanFit motor unit number estimation during Wallerian degeneration after nerve transections

Ist Teil von

• Muscle & nerve, 2020-08, Vol.62 (2), p.239-246

Ort / Verlag

Hoboken, USA: John Wiley & Sons, Inc

Erscheinungsjahr

2020

Quelle

Wiley-Blackwell Full Collection

Beschreibungen/Notizen

• Background Compound muscle action potential (CMAP) scan and MScanFit have been used to understand the consequences of denervation and reinnervation. This study aimed to monitor these parameters during Wallerian degeneration (WD) after acute nerve transections (ANT). Methods Beginning after urgent surgery, CMAP scans were recorded at 1–2 day intervals in 12 patients with ANT of the ulnar or median nerves, by stimulating the distal stump (DS). Stimulus intensities (SI), steps, returners, and MScanFit were calculated. Studies were grouped according to the examination time after ANT. Results were compared with those of 27 controls. Results CMAP amplitudes and MScanFit progressively declined, revealing a positive correlation with one another. SIs were higher in WD groups than controls. Steps appeared or disappeared in follow‐up scans. The late WD group had higher returner% than the early WD and control groups. Conclusions MScanFit can monitor neuromuscular dysfunction during WD. SIs revealed excitability changes in DS.