Details

Autor(en) / Beteiligte

• Qiao, Dou
• Pan, Jun
• Chen, Gongbo
• Xiang, Hao
• Tu, Runqi
• Zhang, Xia
• Dong, Xiaokang
• Wang, Yan
• Luo, Zhicheng
• Tian, Huiling
• Mao, Zhenxing
• Huo, Wenqian
• Zhang, Gongyuan
• Li, Shanshan
• Guo, Yuming
• Wang, Chongjian

Titel

Long-term exposure to air pollution might increase prevalence of osteoporosis in Chinese rural population

Ist Teil von

• Environmental research, 2020-04, Vol.183, p.109264-109264, Article 109264

Ort / Verlag

Netherlands: Elsevier Inc

Erscheinungsjahr

2020

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The associations of long-term exposure to air pollution with osteoporosis are rarely reported, especially in rural China. This study aimed to explore the association among rural Chinese population. A total of 8033 participants (18–79 years) derived from the Henan Rural Cohort Study (n = 39,259) were included in this cross-sectional study. Exposure to air pollutants was estimated using machine learning algorithms with satellite remote sensing, land use information, and meteorological data [including particulate matter with aerodynamic diameters ≤1.0 μm (PM1), ≤2.5 μm (PM2.5), and ≤10 μm (PM10), and nitrogen dioxide (NO2)]. The bone mineral density of each individual was measured by using ultrasonic bone density apparatus and osteoporosis was defined based on the T-score ≤ −2.5. Multiple logistic regression models were used to examine the association of air pollution and osteoporosis prevalence. We observed that per 1 μg/m3 increase in PM1, PM2.5, PM10 and NO2 were associated with a 14.9%, 14.6%, 7.3%, and 16.5% elevated risk of osteoporosis. Compared with individuals in the first quartile, individuals in the fourth quartile had higher odds ratio (OR) of osteoporosis (P-trend < 0.001), the ORs (95% confidence interval) were 2.08 (1.72, 2.50) for PM1, 2.28 (1.90, 2.74) for PM2.5, 1.93 (1.60, 2.32) for PM10, and 2.02 (1.68, 2.41) for NO2. It was estimated that 20.29%–24.36% of osteoporosis cases could be attributable to air pollution in the rural population from China. Long-term exposure to air pollutants were positively associated with high-risk of osteoporosis, indicated that improving air quality may be beneficial to improve rural residents health. •We explored effect of air pollution on osteoporosis in mainland China firstly.•Air pollution have to do with elevated prevalence of osteoporosis in rural China.•20.29%–24.36% of the osteoporosis cases could be attributed to air pollution.•Our findings have great significance on development of environmental health policy.