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Pathogenesis of Macrophage Activation Syndrome and Potential for Cytokine- Directed Therapies

Annual review of medicine, 2015-01, Vol.66 (1), p.145-159

2015

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On the Alert for Cytokine Storm: Immunopathology in COVID‐19

Arthritis & rheumatology (Hoboken, N.J.), 2020-07, Vol.72 (7), p.1059-1063

2020

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Mouse models of systemic juvenile idiopathic arthritis and macrophage activation syndrome

Arthritis research & therapy, 2023-03, Vol.25 (1), p.48-48, Article 48

2023

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Systemic juvenile idiopathic arthritis and macrophage activation syndrome: update on pathogenesis and treatment

Current opinion in rheumatology, 2018-09, Vol.30 (5), p.514-520

2018

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Convergent pathways of the hyperferritinemic syndromes

International immunology, 2018-04, Vol.30 (5), p.195-203

2018

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Systemic autoinflammation with intractable epilepsy managed with interleukin-1 blockade

Journal of neuroinflammation, 2018-02, Vol.15 (1), p.38-38, Article 38

2018

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Macrophage activation syndrome and cytokine-directed therapies

Best practice & research. Clinical rheumatology, 2014-04, Vol.28 (2), p.277-292

2014

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Systemic Juvenile Idiopathic Arthritis–Associated Lung Disease: Characterization and Risk Factors

Arthritis & rheumatology (Hoboken, N.J.), 2019-11, Vol.71 (11), p.1943-1954

2019

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IL-18 as a biomarker linking systemic juvenile idiopathic arthritis and macrophage activation syndrome

Rheumatology (Oxford, England), 2020-02, Vol.59 (2), p.361-366

2020

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Functional Regulation of Macrophage Phenotypes by MicroRNAs in Inflammatory Arthritis

Frontiers in immunology, 2019-09, Vol.10, p.2217-2217

2019

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Whole-Exome Sequencing Reveals Mutations in Genes Linked to Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome in Fatal Cases of H1N1 Influenza

The Journal of infectious diseases, 2016-04, Vol.213 (7), p.1180-1188

2016

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Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation

Nature immunology, 2021-06, Vol.22 (6), p.711

2021

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Adenosine deaminase 2 as a biomarker of macrophage activation syndrome in systemic juvenile idiopathic arthritis

Annals of the rheumatic diseases, 2020-02, Vol.79 (2), p.225

2020

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Identification of Distinct Inflammatory Programs and Biomarkers in Systemic Juvenile Idiopathic Arthritis and Related Lung Disease by Serum Proteome Analysis

Arthritis & rheumatology (Hoboken, N.J.), 2022-07, Vol.74 (7), p.1271-1283

2022

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Population-level single-cell genomics reveals conserved gene programs in systemic juvenile idiopathic arthritis

The Journal of clinical investigation, 2023-11, Vol.133 (22), p.1-18

2023

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Neutrophils From Children With Systemic Juvenile Idiopathic Arthritis Exhibit Persistent Proinflammatory Activation Despite Long-Standing Clinically Inactive Disease

Frontiers in immunology, 2018-12, Vol.9, p.2995-2995

2018

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Complications of complications: diagnosis and treatment of recurrent macrophage activation syndrome in a patient with well-controlled systemic juvenile idiopathic arthritis

Rheumatic & musculoskeletal diseases open, 2023-01, Vol.9 (1), p.e002611

2023

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Spectrum of severity of multisystem inflammatory syndrome in children: an EHR-based cohort study from the RECOVER program

Scientific reports, 2023-11, Vol.13 (1), p.21005-21005, Article 21005

2023

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S100 proteins as potential predictive biomarkers of abatacept response in polyarticular juvenile idiopathic arthritis

Arthritis research & therapy, 2024-06, Vol.26 (1), p.125-12, Article 125

2024

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The IL-18/IFNγ axis in systemic JIA and MAS—new answers, more questions

Rheumatology (Oxford, England), 2021-07, Vol.60 (7), p.3045-3047

Schulert, Grant S

2021

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Differential infection of mononuclear phagocytes by Francisella tularensis: role of the macrophage mannose receptor

Journal of leukocyte biology, 2006-09, Vol.80 (3), p.563-571

2006

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COVID-19 and cytokine storm syndrome: are there lessons from macrophage activation syndrome?

Translational research : the journal of laboratory and clinical medicine, 2021-06, Vol.232, p.1-12

2021

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Molecular Pathways in the Pathogenesis of Systemic Juvenile Idiopathic Arthritis

Rheumatic diseases clinics of North America, 2023-11, Vol.49 (4), p.895-911

2023

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IFN-γ is essential for alveolar macrophage-driven pulmonary inflammation in macrophage activation syndrome

JCI insight, 2021-09, Vol.6 (17)

2021

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New developments related to lung complications in pediatric rheumatic disease

Current opinion in rheumatology, 2023-09, Vol.35 (5), p.273

2023

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Pathogenesis of Macrophage Activation Syndrome and Potential for Cytokine- Directed Therapies

On the Alert for Cytokine Storm: Immunopathology in COVID‐19

Mouse models of systemic juvenile idiopathic arthritis and macrophage activation syndrome

Systemic juvenile idiopathic arthritis and macrophage activation syndrome: update on pathogenesis and treatment

Convergent pathways of the hyperferritinemic syndromes

Systemic autoinflammation with intractable epilepsy managed with interleukin-1 blockade

Macrophage activation syndrome and cytokine-directed therapies

Systemic Juvenile Idiopathic Arthritis–Associated Lung Disease: Characterization and Risk Factors

IL-18 as a biomarker linking systemic juvenile idiopathic arthritis and macrophage activation syndrome

Functional Regulation of Macrophage Phenotypes by MicroRNAs in Inflammatory Arthritis

Whole-Exome Sequencing Reveals Mutations in Genes Linked to Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome in Fatal Cases of H1N1 Influenza

Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation

Adenosine deaminase 2 as a biomarker of macrophage activation syndrome in systemic juvenile idiopathic arthritis

Identification of Distinct Inflammatory Programs and Biomarkers in Systemic Juvenile Idiopathic Arthritis and Related Lung Disease by Serum Proteome Analysis

Population-level single-cell genomics reveals conserved gene programs in systemic juvenile idiopathic arthritis

Neutrophils From Children With Systemic Juvenile Idiopathic Arthritis Exhibit Persistent Proinflammatory Activation Despite Long-Standing Clinically Inactive Disease

Complications of complications: diagnosis and treatment of recurrent macrophage activation syndrome in a patient with well-controlled systemic juvenile idiopathic arthritis

Spectrum of severity of multisystem inflammatory syndrome in children: an EHR-based cohort study from the RECOVER program

S100 proteins as potential predictive biomarkers of abatacept response in polyarticular juvenile idiopathic arthritis

The IL-18/IFNγ axis in systemic JIA and MAS—new answers, more questions

Differential infection of mononuclear phagocytes by Francisella tularensis: role of the macrophage mannose receptor

COVID-19 and cytokine storm syndrome: are there lessons from macrophage activation syndrome?

Molecular Pathways in the Pathogenesis of Systemic Juvenile Idiopathic Arthritis

IFN-γ is essential for alveolar macrophage-driven pulmonary inflammation in macrophage activation syndrome

New developments related to lung complications in pediatric rheumatic disease

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