Details

Autor(en) / Beteiligte

• Fortunato, Allana C.
• Pinheiro, Rafael S.
• Nacif, Lucas S.
• Waisberg, Daniel R.
• Ducatti, Liliana
• Rocha-Santos, Vinicius
• Galvao, Flávio H.F.
• Haddad, Luciana B.P.
• Abdala, Edson
• Song, Alice T.W.
• Terrabuio, Débora R.B.
• Bezerra, Regis O.F.
• Macedo, Rubens A.
• Martino, Rodrigo B.
• Andraus, Wellington
• Carneiro-D'Albuquerque, Luiz A.

Titel

Hepatic Artery Thrombosis in Liver Transplantation in Adult Recipients Using Pediatric Deceased Donors

Ist Teil von

• Transplantation proceedings, 2020-06, Vol.52 (5), p.1332-1335

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2020

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Routinely, pediatric donor (PD) grafts are allocated to pediatric liver transplantation (LT) recipients; however, occasionally they can be allocated for adult recipients (ARs). Some authors reported decreased patient/graft survival and higher vascular complications, such as hepatic artery thrombosis (HAT), in LT in ARs using PDs. It is a retrospective study enrolling 1202 ARs undergoing LT using whole liver grafts during the period of January 2002 to April 2019. The patients were categorized according to donor age in 2 groups: PDs and adult donors (ADs). The variables were collected from the database including the graft to recipient weight ratio (GWRW) and the incidence of HAT and graft primary nonfunction (PNF). The AD group had 1152 patients, and the PD group had 50 patients. PNF occurred in 68 (5.66%) patients, and the distribution between the 2 groups were similar: 65 (5.64%) in the AD group, and 3 (6%) in the PD group (P = .915). HAT was diagnosed in 30 (2.6%) patients in the AD group and in 6 (12%) patients in the PD group. HAT was significantly higher in the PD group (P = .001). In the PD group, the GWRWs among patients diagnosed with HAT were similar (P = .152). HAT is higher in PDs, although it is a viable alternative with satisfactory results. Serial Doppler in the first week and early introduction of platelet antiaggregants and/or anticoagulants may be beneficial, albeit it is not clear if it could reduce the incidence of HAT.