Details

Autor(en) / Beteiligte

• Miqueleiz-Zapatero, Ana
• Alba-Rubio, Claudio
• Domingo-García, Diego
• Cantón, Rafael
• Gómez-García de la Pedrosa, Elia
• Aznar-Cano, Esteban
• Leiva, José
• Montes, Milagrosa
• Sánchez-Romero, Isabel
• Rodríguez-Díaz, Juan Carlos
• Alarcón-Cavero, Teresa

Titel

First national survey of the diagnosis of Helicobacter pylori infection in Clinical Microbiology Laboratories in Spain

Ist Teil von

• Enfermedades infecciosas y microbiologia clinica (English ed.), 2020-11, Vol.38 (9), p.410-416

Erscheinungsjahr

2020

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• INTRODUCTIONThe aim of this study was to know, through a national survey, the methods and techniques used for the diagnosis of Helicobacter pylori (Hp) in the different Clinical Microbiology Services/Laboratories in Spain, as well as antibiotic resistance data. METHODSThe survey requested information about the diagnostic methods performed for Hp detection in Clinical Microbiology laboratories, including serology, stool antigen, culture from gastric biopsies, and PCR. In addition, the performance of antibiotic susceptibility was collected. Data on the number of samples processed in 2016, positivity of each technique and resistance data were requested. The survey was sent by email (October-December 2017) to the heads of 198 Clinical Microbiology Laboratories in Spain. RESULTSOverall, 51 centers from 29 regions answered the survey and 48/51 provided Hp microbiological diagnostic testing. Concerning the microbiological methods used to diagnose Hp infection, the culture of gastric biopsies was the most frequent (37/48), followed by stool antigen detection (35/48), serology (19/48) and biopsy PCR (5/48). Regarding antibiotic resistance, high resistance rates were observed, especially in metronidazole and clarithromycin (over 33%). CONCLUSIONCulture of gastric biopsies was the most frequent method for detection of Hp, but the immunochromatographic stool antigen test was the one with which the largest number of samples were analyzed. Nowadays, in Spain, it concerns the problem of increased antibiotic resistance to 'first-line' antibiotics.