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Linking prescription opioids and infectious diseases
Ist Teil von
The Lancet infectious diseases, 2020-04, Vol.20 (4), p.392-394
Ort / Verlag
United States: Elsevier Ltd
Erscheinungsjahr
2020
Quelle
Elsevier ScienceDirect Journals Complete
Beschreibungen/Notizen
[...]in a previous study,7 the authors showed that the technique needed to prepare controlled-release hydromorphone for injection led to increased contamination with S aureus. [...]unlike other opioids, controlled-release hydromorphone appears to uniquely support the growth of S aureus, similar to the case of T's and blues and P aeruginosa O11.7 Within efforts to address the current opioid crisis, there has been great interest in so-called abuse-deterrent formulations, which discourage injection via diverse mechanisms. More broadly, supply-side strategies to stem opioid prescribing could lead to a shift from prescription drug use to non-prescription opioids, such as heroin and fentanyl, and in turn an increase in fatal overdoses.9 To fully reduce drug-related harms, these interventions need to be coupled with efforts to build treatment capacity for substance use disorders and to implement harm reduction services, such as syringe exchange programmes.