Details

Autor(en) / Beteiligte

• Zhou, Kunfeng
• Shen, Defeng
• Li, Xiao
• Chen, Yuhao
• Hou, Liran
• Zhang, Yishuai
• Sha, Jingquan

Titel

Molybdenum oxide-based metal-organic framework/polypyrrole nanocomposites for enhancing electrochemical detection of dopamine

Ist Teil von

• Talanta (Oxford), 2020-03, Vol.209, p.120507-120507, Article 120507

Ort / Verlag

Netherlands: Elsevier B.V

Erscheinungsjahr

2020

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• To overcome the poor conductivities and promote the application in the biosensors of metal-organic frameworks (MOFs), a simple approach was employed to improve their overall conductivity by adjusting the metal centers of MOFs and coating conductive polypyrrole (PPy) in the work. An unprecedented molybdenum oxide-based three-dimensional MOFs with helical channels (CuTRZMoO4) was synthesized based on MoO4−, Cu2+ ions and 1,2,3-trz for the first time, then combined with PPy to fabricate hybrid composites (CuTRZMoO4@PPy-n) with both advantages. The CuTRZMoO4 modified glassy carbon electrode show high sensitivity for detecting the neurotransmitter dopamine (DA), and the CuTRZMoO4@PPy-2 modified glassy carbon electrode has the highest catalytical activity to DA with the linear detection range from 1 μM to 100 μM and the detection limit of 80 nM (S/N = 3) by differential pulse voltammetry (DPV). Moreover, the developed biosensor has good selectivity, reproducibility and stability. The concept behinds the new architecture to modify electrodes should promote the further development of MOF-based biosensors. A high active, non-noble MOF based biosensing platform by adjusting the metal centers of MOFs and employing conductive polypyrrole (PPy) for enhancing detection of dopamine (DA) was developed for the first time. [Display omitted] •Molybdenum oxide-based metal-organic framework ([Cu3(trz)2(MoO4)2]·H2O) were synthesized.•Adjusting the metal centers of Mo based MOFs and employing conductive PPy to dopamine (DA) detection is discussed.•The CuTRZMoO4@PPy exhibit the excellent detection of DA with wide linear detection range and very low limit of detection.