Details

Autor(en) / Beteiligte

• Bai, Xiaoyun
• Zhang, Bo
• Liu, Miao
• Hu, Xuelian
• Fang, Guozhen
• Wang, Shuo

Titel

Molecularly imprinted electrochemical sensor based on polypyrrole/dopamine@graphene incorporated with surface molecularly imprinted polymers thin film for recognition of olaquindox

Ist Teil von

• Bioelectrochemistry (Amsterdam, Netherlands), 2020-04, Vol.132, p.107398-107398, Article 107398

Ort / Verlag

Netherlands: Elsevier B.V

Erscheinungsjahr

2020

Quelle

MEDLINE

Beschreibungen/Notizen

• •A novel MIECS was constructed for OLA detection.•Dopamine@graphene composites and PPy were explored for enlarging the MIECS signal.•The MIECS used two properties of dopamine: adhesion and functional monomers.•The developed sensor displayed high sensitivity, good selectivity, reproducibility. In this paper, an advanced molecularly imprinted electrochemical sensor (MIECS) based on electropolymerized olaquindox (OLA) surface molecularly imprinted polymer thin film on a modified glassy carbon electrode (GCE) was developed for the detection of OLA. It was fabricated by coating dopamine@graphene (DGr) on GCE, then electropolymerizing pyrrole (Py) and molecularly imprinted polymers (MIPs). Graphene (Gr) was introduced for improving conductivity and sensitivity. Dopamine (DA) was used for dispersion and adhesion of Gr. Polypyrrole (PPy) could fix DGr and enhance the current response evidently. The established sensor could selectively recognize OLA but not the analogs of OLA. Some essential parameters controlling the performance of the developed sensor were investigated and optimized. Under optimal conditions, the linear relationship between the current intensity and OLA concentration was obtained from 50 nmol L−1 to 500 nmol L−1 with a limit of detection (LOD) of 7.5 nmol L−1. Analytical results of OLA based on the developed MIECS for fish and feedstuffs showed a good agreement with the results based on high performance liquid chromatography (HPLC).