Details

Autor(en) / Beteiligte

• Kirkpatrick, Carol F.
• Bolick, Julie P.
• Kris-Etherton, Penny M.
• Sikand, Geeta
• Aspry, Karen E.
• Soffer, Daniel E.
• Willard, Kaye-Eileen
• Maki, Kevin C.

Titel

Review of current evidence and clinical recommendations on the effects of low-carbohydrate and very-low-carbohydrate (including ketogenic) diets for the management of body weight and other cardiometabolic risk factors: A scientific statement from the National Lipid Association Nutrition and Lifestyle Task Force

Ist Teil von

• Journal of clinical lipidology, 2019-09, Vol.13 (5), p.689-711.e1

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2019

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Historically, low-carbohydrate (CHO) and very-low-CHO diets have been used for weight loss. Recently, these diets have been promoted for type 2 diabetes (T2D) management. This scientific statement provides a comprehensive review of the current evidence base available from recent systematic reviews and meta-analyses on the effects of low-CHO and very-low-CHO diets on body weight, lipoprotein lipids, glycemic control, and other cardiometabolic risk factors. In addition, evidence on emerging risk factors and potential safety concerns of low-CHO and very-low-CHO diets, especially for high-risk individuals, such as those with genetic lipid disorders, was reviewed. Based on the evidence reviewed, low-CHO and very-low-CHO diets are not superior to other dietary approaches for weight loss. These diets may have advantages related to appetite control, triglyceride reduction, and reduction in the use of medication in T2D management. The evidence reviewed showed mixed effects on low-density lipoprotein cholesterol levels with some studies showing an increase. There was no clear evidence for advantages regarding effects on other cardiometabolic risk markers. Minimal data are available regarding long-term (>2 years) efficacy and safety. Clinicians are encouraged to consider the evidence discussed in this scientific statement when counseling patients on the use of low-CHO and very-low-CHO diets. •Low- and very-low-carbohydrate diets are not superior to other weight loss diets.•May have advantages on appetite and reduced triglyceride and diabetes medication.•Mixed effects on low-density lipoprotein cholesterol levels.•No clear evidence for advantages related to other cardiometabolic risk markers.