Details

Autor(en) / Beteiligte

• Da Silva, M. S
• Weber, M. N.
• Baumbach, L. F.
• Cibulski, S. P.
• Budaszewski, R. F.
• Mósena, A. C. S.
• Canova, R.
• Varela, A. P. M.
• Mayer, F. Q.
• Canal, Cláudio W.

Titel

Highly divergent cattle hepacivirus N in Southern Brazil

Ist Teil von

• Archives of virology, 2019-12, Vol.164 (12), p.3133-3136

Ort / Verlag

Vienna: Springer Vienna

Erscheinungsjahr

2019

Quelle

SpringerLink Journals - AutoHoldings

Beschreibungen/Notizen

• The genus Hepacivirus includes 14 species ( Hepacivirus A – N ). In this study, we determined a partial genome sequence of a highly divergent bovine hepacivirus (hepacivirus N, HNV) isolate from cattle in Southern Brazil. Previously described HNV isolates have shared 80–99.7% nucleotide sequence identity in the NS3 coding region. However, the sequence determined in this study had 72.6% to 73.8% nucleotide sequence identity to known HNV NS3 sequences. This high divergence could be seen in a phylogenetic tree, suggesting that it represents a new genotype of HNV. These data expand our knowledge concerning the genetic variability and evolution of hepaciviruses.