Details

Autor(en) / Beteiligte

• Kenny, Ciarán, PhD, MSc, BSc, PG Dip Stats
• Regan, Julie, PhD, MSc, BSc
• Balding, Lucy, BA MB BCh BAO MRCPI MSc
• Higgins, Stephen, MB BCh BAO NUI MRCPI
• O’Leary, Norma, MB BCh BAO BMedSc MRCPI MD
• Kelleher, Fergal, MB BCh NUI
• McDermott, Ray, MB BCh BAO PhD MBA MRCPI
• Armstrong, John, MD FRCPI DABR FFRRCSI
• Mihai, Alina, MD, MSc
• Tiernan, Eoin, MB BCH BAO MD FRCPI
• Westrup, Jennifer, MD, BCh, BAO
• Thirion, Pierre, MD, FFRRCSI
• Walsh, Declan, MSc FACP FRCP (Edin) FTCD

Titel

Dysphagia prevalence and predictors in cancers outside the head, neck, and upper gastrointestinal tract

Ist Teil von

• Journal of pain and symptom management, 2019-12, Vol.58 (6), p.949-958.e2

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2019

Quelle

Applied Social Sciences Index & Abstracts (ASSIA)

Beschreibungen/Notizen

• AbstractContextDysphagia is usually associated with malignancies of the head, neck, and upper gastrointestinal tract, but also occurs in those with tumours outside anatomic swallow regions. It can lead to aspiration pneumonia, malnutrition, reduced quality of life, and psychosocial distress. No studies have yet reliably described dysphagia prevalence in those with malignancies outside anatomic swallow regions. ObjectiveTo establish the prevalence and predictors of dysphagia in adults with solid malignancies outside the head, neck, and upper gastrointestinal tract. MethodsA cross-sectional, observational study using consecutive sampling was conducted. There were 385 participants (mean age 66 ±12 years) with 21 different primary cancer sites from two acute hospitals and one hospice. Locoregional disease was present in 33%, metastatic in 67%. Dysphagia was screened by empirical questionnaire and confirmed through swallow evaluation. Demographic and clinical predictors were determined by univariate and multivariate binary regression. ResultsDysphagia occurred in 19% of those with malignancies outside anatomic swallow regions. Prevalence was 30% in palliative care and 32% in hospice care. Dysphagia was most strongly associated with cough, nausea, and worse performance status. It was also associated with lower quality of life and nutritional difficulties. ConclusionDysphagia was common and usually undiagnosed prior to study participation. It occurred at all disease stages, but coincided with functional decline. It may therefore represent a cancer frailty marker. Oncology and palliative care services should routinely screen for this symptom. Timely dysphagia identification and management may improve patient wellbeing and prevent adverse effects like aspiration pneumonia and weight loss.