Details

Autor(en) / Beteiligte

• Willmitzer, Florian
• Del Chicca, Francesca
• Kircher, Patrick R
• Wang-Leandro, Adriano
• Kronen, Peter W
• Verdino, Dagmar
• Rüfenacht, Daniel
• Porcellini, Beat
• Richter, Henning

Titel

Diffusion-weighted and perfusion-weighted magnetic resonance imaging of the prostate gland of healthy adult dogs

Ist Teil von

• American journal of veterinary research, 2019-09, Vol.80 (9), p.832-839

Ort / Verlag

United States

Erscheinungsjahr

2019

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• To describe diffusion and perfusion characteristics of the prostate gland of healthy sexually intact adult dogs as determined by use of diffusion-weighted and perfusion-weighted MRI. 12 healthy sexually intact adult Beagles. Ultrasonography of the prostate gland was performed. Subsequently, each dog was anesthetized, and morphological, diffusion-weighted, and perfusion-weighted MRI of the caudal aspect of the abdomen was performed. The apparent diffusion coefficient was calculated for the prostate gland parenchyma in diffusion-weighted MRI images in the central ventral and peripheral dorsal areas. Perfusion variables were examined in multiple regions of interest (ROIs) in the ventral and dorsal areas of the prostate gland and in the gluteal musculature. Signal intensity was determined, and a time-intensity curve was generated for each ROI. Results of ultrasonographic examination of the prostate gland revealed no abnormalities for any dog. Median apparent diffusion coefficient of the prostate gland was 1.51 × 10 mm /s (range, 1.04 × 10 mm /s to 1.86 × 10 mm /s). Perfusion-weighted MRI variables for the ROIs differed between the prostate gland parenchyma and gluteal musculature. Results provided baseline information about diffusion and perfusion characteristics of the prostate gland in healthy sexually intact adult dogs. Additional studies with dogs of various ages and breeds, with and without abnormalities of the prostate gland, will be necessary to validate these findings and investigate clinical applications.