Details

Autor(en) / Beteiligte

• Liu, Anyi
• Han, Qingshuai
• Zhang, Xiaofeng
• Li, Buhong
• Huang, Qiufeng

Titel

Transition-Metal-Controlled Synthesis of 11H‑Benzo[a]carbazoles and 6‑Alkylidene‑6H‑isoindo[2,1‑a]indoles via Sequential Intermolecular/Intramolecular Cross-Dehydrogenative Coupling from 2‑Phenylindoles

Ist Teil von

• Organic letters, 2019-09, Vol.21 (17), p.6839-6843

Ort / Verlag

American Chemical Society

Erscheinungsjahr

2019

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A catalyst-controlled synthesis of 11H-benzo­[a]­carbazoles and 6-alkylidene-6H-isoindo­[2,1-a]­indoles is described. Pd­(OAc)2 favored 6-alkylidene-6H-isoindo­[2,1-a]­indoles via intramolecular C–H/N–H CDC reaction, while [Cp*RhCl2]2 led to 11H-benzo­[a]­carbazoles through intramolecular C–H/C–H CDC reaction. Moreover, the synthesis of 11H-benzo­[a]­carbazoles via sequential intermolecular ortho C–H/olefin coupling and intramolecular C3-H/olefin coupling from 2-phenylindoles and alkenes can be operated in one pot.