American journal of respiratory and critical care medicine, 2019-12, Vol.200 (11), p.1439-1441
2019
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Details
- Autor(en) / Beteiligte
- Titel
- Network Analysis of Genome-Wide Association Studies for Chronic Obstructive Pulmonary Disease in the Context of Biological Pathways
- Ist Teil von
- American journal of respiratory and critical care medicine, 2019-12, Vol.200 (11), p.1439-1441
- Ort / Verlag
- United States: American Thoracic Society
- Erscheinungsjahr
- 2019
- Quelle
- Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
- Beschreibungen/Notizen
- Chronic obstructive pulmonary disease (COPD) is a common respiratory disease projected to be the third lead big cause of death by 2020. The main risk factor is tobacco smoking and environmental exposures. Furthermore, host factors like abnormal lung development, genetic abnormalities and accelerated aging increase susceptibility to COPD. However, the causal mechanisms remain poorly understood.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1073-449XeISSN: 1535-4970DOI: 10.1164/rccm.201904-0902LETitel-ID: cdi_proquest_miscellaneous_2265781116
- Format
- –
- Schlagworte
- Aging, Chronic obstructive pulmonary disease, Gene Regulatory Networks - genetics, Genetic disorders, Genetic Predisposition to Disease - genetics, Genome-Wide Association Study, Humans, Metabolic Networks and Pathways - genetics, Polymorphism, Single Nucleotide - genetics, Pulmonary Disease, Chronic Obstructive - genetics, Pulmonary Disease, Chronic Obstructive - metabolism, Respiratory diseases, Smoking, Tobacco