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Details

Autor(en) / Beteiligte
Titel
Glycaemic control in individuals with type 1 diabetes using an open source artificial pancreas system (OpenAPS)
Ist Teil von
  • Diabetes, obesity & metabolism, 2019-10, Vol.21 (10), p.2333-2337
Ort / Verlag
Oxford, UK: Blackwell Publishing Ltd
Erscheinungsjahr
2019
Link zum Volltext
Quelle
Wiley Online Library All Journals
Beschreibungen/Notizen
  • Open source artificial pancreas systems (OpenAPS) have gained considerable interest in the diabetes community. We analyzed continuous glucose monitoring (CGM) records of 80 OpenAPS users with type 1 diabetes (T1D). A total of 19 495 days (53.4 years) of CGM records were available. Mean glucose was 7.6 ± 1.1 mmol/L, time in range 3.9–10 mmol/L was 77.5 ± 10.5%, <3.9 mmol/L was 4.3 ± 3.6%, <3.0 mmol/L was 1.3 ± 1.9%, >10 mmol/L was 18.2 ± 11.0% and > 13.9 mmol/L was 4.1 ± 4.0%, respectively. In 34 OpenAPS users, additional CGM records were obtained while using sensor‐augmented pump therapy (SAP). After changing from SAP to OpenAPS, lower mean glucose (−0.6 ± 0.7; P < 0.0001), lower estimated HbA1c (−0.4 ± 0.5%; P < 0.0001), higher time in range 3.9–10 mmol/L (+9.3 ± 9.5%; P < 0.0001), less time < 3.0 mmol/L (−0.7 ± 2.2%; P = 0.0171), lower coefficient of variation (−2.4 ± 5.8; P = 0.0198) and lower mean of daily differences (−0.6 ± 0.9 mmol/L; P = 0.0005) was observed. Glycaemic control using OpenAPS was comparable with results of more rigorously developed and tested AP systems. However, OpenAPS was used by a highly selective, motivated and technology‐adept cohort, despite not being approved for the treatment of individuals with T1D.
Sprache
Englisch
Identifikatoren
ISSN: 1462-8902
eISSN: 1463-1326
DOI: 10.1111/dom.13810
Titel-ID: cdi_proquest_miscellaneous_2253281978

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