Details

Autor(en) / Beteiligte

• Qiao, Baokun
• Li, Chunyang
• Zhao, Xiaowei
• Yin, Yanli
• Jiang, Zhiyong

Titel

Enantioselective reduction of azaarene-based ketones via visible light-driven photoredox asymmetric catalysis

Ist Teil von

• Chemical communications (Cambridge, England), 2019-07, Vol.55 (52), p.7534-7537

Ort / Verlag

England: Royal Society of Chemistry

Erscheinungsjahr

2019

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• An enantioselective reduction of azaarene-based ketones through photoredox asymmetric catalysis is reported. With a transition metal-free dual catalytic system including a chiral phosphoric acid and a photosensitizer DPZ mediated by visible light, the transformations involved a tandem process involving double single-electron-transfer reductions and enantioselective protonation, providing valuable chiral alcohols in high yields (up to >99%) with good to excellent enantioselectivities (up to 97% ee).