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Details

Autor(en) / Beteiligte
Titel
Large-scale ruminant genome sequencing provides insights into their evolution and distinct traits
Ist Teil von
  • Science (American Association for the Advancement of Science), 2019-06, Vol.364 (6446)
Ort / Verlag
United States: The American Association for the Advancement of Science
Erscheinungsjahr
2019
Quelle
American Association for the Advancement of Science
Beschreibungen/Notizen
  • The ruminants are one of the most successful mammalian lineages, exhibiting morphological and habitat diversity and containing several key livestock species. To better understand their evolution, we generated and analyzed de novo assembled genomes of 44 ruminant species, representing all six Ruminantia families. We used these genomes to create a time-calibrated phylogeny to resolve topological controversies, overcoming the challenges of incomplete lineage sorting. Population dynamic analyses show that population declines commenced between 100,000 and 50,000 years ago, which is concomitant with expansion in human populations. We also reveal genes and regulatory elements that possibly contribute to the evolution of the digestive system, cranial appendages, immune system, metabolism, body size, cursorial locomotion, and dentition of the ruminants.

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