Details

Autor(en) / Beteiligte

• Rabinowitz, Jonathan
• Schooler, Nina R
• Brown, Brianne
• Dalsgaard, Mads
• Engelhardt, Nina
• Friedberger, Gretchen
• Kinon, Bruce J
• Lee, Daniel
• Ockun, Felice
• Mahableshwarkar, Atul
• Tsai, Joyce
• Williams, Janet B.W.
• Sauder, Colin
• Yavorsky, Christian

Titel

Consistency checks to improve measurement with the Montgomery-Asberg Depression Rating Scale (MADRS)

Ist Teil von

• Journal of affective disorders, 2019-09, Vol.256, p.143-147

Ort / Verlag

Netherlands: Elsevier B.V

Erscheinungsjahr

2019

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• •A set of expert consensus derived consistency flags for the MADRS.•Flags elaborated in paper can be applied.•Flags represent actual patterns of potential inconsistencies found.•Application of flags to ratings may improve reliability of ratings and validity of trials. International Society for CNS Clinical Trials and Methodology convened an expert Working Group that assembled consistency/inconsistency flags for the Montgomery-Asberg Depression Rating Scale (MADRS). Twenty-two flags were identified. Seven flags are believed to be strong flags that suggest that a thorough review of rating is warranted. The flags were applied to assessments derived from the NEWMEDS data repository. Almost 65% of ratings had at least one inconsistency flag raised and 22% had two or more. Application of flags to clinical ratings may improve reliability of ratings and validity of trials.