Details

Autor(en) / Beteiligte

• Nguyen, Tu-Son
• Nguyen, Thi Lien Huong
• Pham, Thi Thuy Van
• Hua, Susan
• Ngo, Quy Chau
• Li, Shu Chuen

Titel

Impact of pharmaceutical care in the improvement of medication adherence and quality of life for COPD patients in Vietnam

Ist Teil von

• Respiratory medicine, 2019-07, Vol.153, p.31-37

Ort / Verlag

England: Elsevier Ltd

Erscheinungsjahr

2019

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Medication adherence is an important factor in the management of chronic obstructive pulmonary disease (COPD). However, the rate of non-adherence to medications is high in COPD and is associated with worsened clinical outcomes and health-related quality of life for patients. Our study aimed to evaluate the impact of a pharmaceutical care program led by pharmacists in the improvement of medication adherence and quality of life for COPD patients in Vietnam. A pre- and post-intervention study was conducted over 12 months. Pharmacists provided brief counselling which focused on the role of COPD medications and the importance of adherence. Morisky Medication Adherence Scale was used to evaluate patients’ adherence. Quality of life was assessed using the EQ-5D-5L questionnaire and clinical outcomes were evaluated by symptom scores. These outcomes were reassessed at baseline (T0), after 3 months (T1), 6 months (T2) and 12 months (T3). Study participants consisted of 211 COPD patients (mean age: 66.6 ± 8.2 years). The percentage of patients with good adherence significantly increased from 37.4% to 53.2% (p < 0.001) after the program. Mean medication adherence scores improved from 6.7 (T0) to 7.4 (T2) and 7.4 (T3) (p < 0.001). EQ-5D-5L index values also increased from 0.47 (T0) to 0.59 (T3) (p < 0.001). There was no significant change in symptom scores across the duration of the study. Medication adherence and quality of life of COPD patients improved considerably after implementation of a pharmaceutical care program, thus supporting a vital role for pharmacists alongside physicians in the management of COPD. •Before the pharmaceutical care program, the adherence level was low.•Post-intervention, patients' medication adherence improved significantly.•The scores of patients' quality of life also increased considerably.•Clinical state of patients was stable across the duration of the study.