Details

Autor(en) / Beteiligte

• Wang, Wei
• Zhu, Haofu
• Liu, Shuya
• Zhao, Zhiguo
• Zhang, Liang
• Hao, Jingcheng
• Wang, Yao

Titel

Chalcogen–Chalcogen Bonding Catalysis Enables Assembly of Discrete Molecules

Ist Teil von

• Journal of the American Chemical Society, 2019-06, Vol.141 (23), p.9175-9179

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2019

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Despite the observation of noncovalent interactions between chalcogen atoms in X-ray crystal structures, catalysis that harnesses the power of such chalcogen–chalcogen bonding interactions to produce advanced molecules remains an unresolved problem. Here, we show that a class of extraordinary chalcogen-bonding catalysts enables assembly of discrete small molecules including three β-ketoaldehydes and one indole, leading to the construction of N-heterocycles in a highly efficient manner. The strong activation ability of these rationally designed catalysts provides a general solution to the intrinsic limitations of chalcogen bonding catalysis.